Warrington-based primary care property development business Assura is to change its corporate structure with the creation of a parent company headquartered in the UK.
The business said it plans to move to a UK domicile from Guernsey to "develop even better commercial relationships" with the NHS and GPs.
It added this will also reduce some of its administrative costs.
It will establish Assura plc, which will be incorporated in the UK and also a UK tax resident, and be the head of the group.
Assura said the move is not expected to have any material impact on the tax it pays.
Simon Laffin, chairman of Assura, said: "Assura is the UK's leading developer and owner of GP surgeries. We have been listed on the London Stock Exchange since 2003 and registered in the UK for tax purposes since 2008.
"Our proposed conversion to a full English domiciled plc will remove any confusion as to our status and reinforce our commitment to serving Britain's primary care sector and the National Health Service."